Beta-Hydroxybutyrate (BHB) is naturally ketone body that is produced when free fatty acids are broken down in the liver. The other two types of Ketone bodies are acetoacetate (AcAc) and acetone. Ketones provide pure energy to fuel the human brain and other tissues. The elevation in ketones in your blood have been a rapidly emerging area of research and studies are continuing to show improvements in performance, brown adipose tissue, and several other possible applications.
The liver is always producing ketones to some small degree and they are always present in the bloodstream. Under normal dietary conditions, ketone concentrations are simply too low to be of any significant benefit. A ketogenic diet and exogenous ketone supplements will increase the amount of ketone in your body. The idea that ketones are “toxic” is ridiculous. Ketones are a normal physiological substance that play many important roles in the human body.
Under normal circumstances, our bodies primarily use glucose as fuel. When carbohydrates are
not readily available (such as in the case of prolonged fasting, carbohydrate restriction, or prolonged exercise), the body shifts to burning fat for fuel. However, the brain and central nervous system can’t use fat for energy, and consequently, the body is forced to turn to an “alternate fuel source” ketones, which the liver creates from fats via the process of ketogenesis. These ketones are then released into the blood Ketones not only fuel the brain, but are also used by skeletal and cardiac muscles. Supplementing with BHB (ketones) can help accelerate ketosis, provide the benefits of elevated blood ketone levels, and enhance keto adaptation with or without following a ketogenic diet.
Supplementing with BHB provides many benfits. Here is a list of the clinically researched benefits of supplementing with the correct dosage of BHB:
1. Accelerated state of Ketosis - Oral BHB salts significantly increase plasma ketones. (1, 2) Compared to various ketosis strategies, oral BHB salts help achieve ketosis quicker and provide a safe and effective regimen to maximize the benefits of low carb/ketogenic diets.
2. Increased Mental Clarity/Focus - Elevated ketone bodies replace glucose as the major energy substrate for the brain and may be neuroprotective, helping preserve cognitive function.(3,4) Clinical data supports the ability of oral BHB salt to significantly improve focus.
3. Increased Energy - In data provided by Burgess, BHB produces more energy than glucose( 13 ATP/C 2 versus 12 67 ATP/C 2 and increases the free energy released from ATP hydrolysis.(5)
4. Enhanced Athletic Performance - Oral exogenous ketones increase plasma BHB levels and fat oxidation, reduce glycolysis and plasma lactate. This maximizes endurance in athletes by altering fuel preference and improves glycogen synthesis.(6-8)
5. Increased Satiety - Exogenous ketones boost blood BHB levels, which increases satiety and improves body composition. (9)
 B.J. Stubbs, P. J. Cox, et al., Frontiers in Physiology, 2017, 8.
 B. Plecko , S. Stoeckler Ipsiroglu , E. Schober , et al., Pediatric Research, 2002, 52(2):301.
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 A. J. Murray, N. S. Knight, M. A. Cole, et al., FASEB J. 2016, 30, 4021 4032.
 S. C. Burgess, K. Iizuka , N. H. Jeoung , et al. Journal of Biological Chemistry, 2008, 283(3):1670
 P. J. Cox, T. Kirk, T. Ashmore , et al., Cell Metabolism, 2016, 24, 256 268.
 M. Evans, K. E. Cogan and B. Egan, J Physiol., 2017, 595(9):2857.
 D. A. Holdsworth , P. J. Cox, T. Kirk, et al., Medicine & Science in Sports & Exercise, 2017, 49(9):1789.
 B. J. Stubbs, P. J. Cox, R.D. Evans, et al., Obesity, 2017, 0(0), 1 5.
BHB Salts and exogenous ketone supplements are literally changing the supplement industry. These products are pretty new and a little more expensive than other supplements. But I’d rather pay for something that works then spend tons of money chasing products that claim to work. One of the most popular ketone supplements is Ketōnd. You can check out our review here.
On this website you will be able to learn from our research, the scientific research behind the ingredients in the best ketone supplements, what scams to avoid and where to get the best prices on the best supplements!
Ketōnd has been pioneering and perfecting ketone supplement longer than most "keto" brands have been around. Year after year, Ketōnd Advanced Blend has never settled when it comes to creating the MOST EFFECTIVE, BEST TASTING, ALL NATURAL ketone supplements available. They have continued to improve their formula while holding true to their commitment to offer the cleanest, highest perfoming, best tasting ketone drink available at an unbeatable price.
This past year, Ketond spend 1000's of hours researching, testing and developing changes to their origing Advanced Ketone Blend. We were able to get some samples and not only did we see and feel better results, the taste was AMAZING! It's on a completely different level than any other ketone drink. Since each serving of Ketond is therapeutically dosed at 11.7g of BHB, there’s no need to swallow twenty underdosed keto pills. On top of that there are ZERO artificial ingredients or flavors and Ketond is committed to 100% ingredient transparency.
After testing and reviewing countless ketone supplement this year, no other product came close to Ketond Advanced Blend. In the areas of taste, results and value - Ketond was off the charts amazing! There has never been a better time that right now to start losing weight. Ketond provides you with a formula guaranteed to help you lose weight or you get your money back. And we just can’t find a better product… Otherwise, we’d put it here in the #1 spot!
BioMAX by Ketōnd was at one time our #1 Rated Ketone Supplement and held that ranking for almost a year. The feedback was so positive from customers and reviewers, and the weight loss results so impressive that we thought something was up. So we pulled it down and sent it to a lab to have it tested and analyzed. The results we received solidified the fact that BioMAX is just one of the best ketone supplements we have reviewed. In fact, it is so cutting edge that other ketone supplement brands are just now starting to use it's primary ingredient, D-BHB, as the stand alone ingredient for their products. They have performed clinical studies proving that D-BHB causes drastic weight loss. So, how is this product truly different than our #1 Ranked Ketone Advanced Blend? Let's take a closer look...Ketōnd BioMAX is a Hardcore Ketone Weight Loss Supplement
That's right. Unlike the clinically studied ketone supplement that only uses 6,000mg of D-BHB per serving (and tastes terrible) BioMAX uses 11,700mg of D-BHB plus contains 4 powerful weight loss ingredients. What is D-BHB? The ketone BHB is made up of two molecules, the D-BHB molecule and the L-BHB molecule. While every other ketone supplement contains a 50/50 of D and L BHB, BioMAX is 100% D-BHB. D-BHB is the ketone that is produced naturally by the liver (endogenously), which is why our D-BHB is absorbed immediately providing instant fuel for your brain and your body. With it's industry leading dosage of D-BHB as well as other provenweight loss ingredients, BioMAX really is a weight loss juggernaut.
The only reasons why BioMAX is ranked #2 is that it is more expensive and the taste of Ketond Advanced Blend is just on a totally different level. That’s the only reason we’ve knocked it back to the #2 slot. However, most people spend 3x more on soda or coffee each day and since it contains 2x the amount of D-BHB as the leading supplement we feel like a product like this is justified in pricing. It also comes with a 100% Money-Back Guarantee. So if you want to get started with a heavy hitter, then we recommend BioMAX from Ketond.
RELOADED by Reloaded Labs is literally the most groundbreaking new Nootropic Ketone supplement we have seen in the past 24 months. We received our sample packs last week and let me tell you that everyone here is IN LOVE with this product.
The way it tastes, the way it makes you feel, the clean, crash-free energy, the overall sense of well-being and focus. I mean we could go on and on but you've really got to try this ketone supplement for yourself to fully appreciate it. So, what makes RELOADED work so well?
You are probably already familiar with the cognitive benefits of BHB, but Teacrine™ and Dynamine™ are easily the most effective and safest energy delivering compounds available. When you combine these two compounds you get instant and sustained energy release. There's no spike followed by a "crash and burn"..
Pruvit Keto//OS (Ketone Operating System) MAX has come a long way since it was introduced. Last year, in 2018, Pruvit reformulated a lot of their products to include their new BHB blend called MAX BHB. MAX BHB is the bioidentical form of BHB called D-BHB.
These are the "new generation" of BHB that are being used in the top-rated ketone supplements this year. In fact it is used in Ketond BioMAX which is this year's #1 rated keto supplement.
D-BHB is an amazing ingredient. When dosed properly, it hits you fast and gives you a great boost in energy and cognition. What we don't know is the amount of D-BHB used in Keto//OS Max.
Everything is hidden in a proprietary blend. This is why it is ranked #4 on this years list. Well that and the price.
Twenty servings of Max will set you back $130 / $6.50 per serving. If you are taking 2 servings per day, which Pruvit recommends for “optimal performance” a one month supply will cost you a whopping $390!!
Pruvit has launched some pretty unique products in the past year. One of them is Keto//OS NAT which they "claim" that its ketone salts are created through a "fermented process". Now I have spoked to a lot of companies that import and distribute BHB salts and NONE of them are familiar with "fermented BHB salts".
In fact, I heard that they might have been tested to see if any live cultures existed. If these were fermented then live cultures would show up during an analysis. They found that NAT contained no live cultures. So, for me, the hunt for these elusive "fermented ketones" continues.
Apart from that this keto supplement contains an unspecified dosage of R-BBHB aka D-BHB. This is the bioidentical form of BHB, which are the same form that are NATurally produced by the body. These are the "new generation" of BHB that are being used in the top-rated ketone supplements this year. In fact it is used in Ketond BioMAX which is this year's #1 rated keto supplement.
Perfect Keto Base is also a relatively new ketone supplement. Perfect Keto is marketed as a supplement that will help you “Get Into Ketosis” and promotes “Effortless Fat Loss”.
While we do love ketone supplements, these are two marketing gimmicks that we have an issue with.
Exogenous ketones ie ketone supplements elevate your blood ketone levels. They don’t necessarily put you in a state of ketosis or induce ketogenesis – which is in a nutshell the conversion of fat into ketones by the liver. What Ketones have been shown to do is suppress your appetite.
So, I don’t know if it’s “wishful thinking” or “enhanced marketing claims” but if you are looking for “effortless fat loss” then simply taking Perfect Keto and expecting a miracle might leave you feeling hustled. Perfecto Keto sells for $59 for 15 servings, so about $4 per serving.
Pruvit Keto//OS (Ketone Operating System) is a multi-level marketing company whose primary products are different variations of ketone supplements. Keto OS 3.0 is similar to the 2.1 but contains no MCT powder and comes in a (very bland) chocolate flavor.
Pruvit doesn't disclose the amount of ketones (bhb salts) that are in each serving of any of their products. In fact, right now on their website they don't show ANY of the ingredients in Keto//OS 3.0. Instead of being open about ingredients, they are all put into “proprietary blends”.
When you order Keto//OS 3.0 you literally have NO idea how much ketones, or any of the other ingredients you are getting in each serving. Not only that but because of the Multi Level Marketing Model, these products are REALLY expensive.
Thirty servings of Keto OS 3.0 will set you back $160 / $5.33 per serving. If you are taking 2 servings per day, which Pruvit recommends for “optimal performance” a one month supply will cost you a whopping $320!!